Thanksgiving leftovers may be more plentiful this year, with around one in eight American adults reportedly taking appetite-suppressing drugs such as Ozempic or Wegovy. These medications, known as GLP-1 agonists, mimic natural hormones that induce feelings of fullness, potentially altering holiday eating habits.
Morgan Williams, a 29-year-old mother from Nebraska, usually enjoys green bean casserole on Turkey Day. However, since starting a GLP-1 drug in April to manage polycystic ovary syndrome (PCOS), she has lost 70 pounds and finds large portions overwhelming. “I used to go back for seconds, but now I’m satisfied after just a few bites,” she told USA Today, adding she often picks up a dish without eating it to avoid hurting feelings.
According to a KFF survey, an estimated 12% of US adults currently take a GLP-1 drug, with usage doubling among both men and women in the past year, per the Gallup National Health and Well-Being Index. While Wegovy is approved for weight loss and Ozempic for type 2 diabetes, both belong to the same class of medications.
Williams acknowledged a lingering stigma around these drugs. “There’s definitely some anxiety that comes with knowing people might have opinions or make comments,” she said. Sabina Hemmi, founder of GLP Winner, advised family members to avoid commenting on reduced appetite, noting that food is a cultural language and holidays may look different but remain special.
