Food Chemistry Expert Highlights Cholesterol-Busting Foods
A leading food chemistry professor has revealed that certain foods and drinks with traditionally poor reputations could be instrumental in cutting cholesterol and boosting cardiovascular health. Ioannis Zabetakis, associate professor of food chemistry at the University of Limerick, emphasises that not all cholesterol is detrimental and that dietary choices can significantly influence heart disease risk.
Understanding Cholesterol: The Good and The Bad
Professor Zabetakis explains the critical distinction between low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol. LDL, often labelled as "bad" cholesterol, contributes to fatty deposits in arteries, increasing the risk of heart attacks and strokes. In contrast, HDL cholesterol performs vital protective functions by removing excess LDL from tissues and arteries, transporting it to the liver for elimination, and safeguarding artery walls from blockages.
The ratio of HDL to LDL is a key determinant of cardiovascular disease risk. A higher HDL-to-LDL ratio correlates with lower risk, while a lower ratio indicates heightened vulnerability. Lifestyle modifications such as regular exercise, smoking cessation, and weight management can positively shift this ratio. However, dietary interventions also play a crucial role, primarily by reducing inflammation—a major contributor to cardiovascular issues.
Four Dietary Champions for Heart Health
Professor Zabetakis identifies four specific food and drink categories that can enhance HDL ratios, diminish inflammation, and promote heart health:
- Fruits and Vegetables: Diets rich in fruits and vegetables are associated with elevated HDL levels, improved total cholesterol ratios, lower blood pressure, and healthier blood sugar levels. These foods neutralise free radicals—unstable molecules that cause cellular damage and inflammation—thereby enabling HDL cholesterol to function effectively in clearing LDL and protecting arteries.
- Oily Fish and Olive Oil: Salmon, sardines, tuna, and olive oil are abundant in polar lipids, a type of fat that rapidly enters the bloodstream. These lipids excel at reducing inflammation and preventing platelet aggregation, which helps maintain balanced cholesterol ratios and lowers cardiovascular risk. Cell and animal studies confirm that polar lipid-rich diets can inhibit blood clot formation.
- Fermented Dairy Products: Yogurt, kefir, and cheese undergo fermentation, breaking down lipids into smaller compounds with enhanced anti-inflammatory properties compared to milk. These products are also rich in polar lipids, offering substantial cardiovascular benefits. Research indicates that consuming just 20 grams of fermented dairy daily can modestly reduce heart disease risk.
- Red Wine: Contrary to common perception, moderate red wine consumption—equivalent to one to two small glasses per day—is linked to better HDL ratios. Red wine contains polar lipids that reduce inflammation in small quantities. However, excessive intake negates these benefits due to alcohol's pro-inflammatory effects. Non-alcoholic wines also contain polar lipids, providing comparable clot-prevention advantages without alcohol-related risks.
The Critical Role of Moderation
Professor Zabetakis stresses the importance of moderation, particularly with alcohol. While red wine's polar lipids offer benefits, overconsumption can lead to adverse health outcomes, including increased cancer risk. The World Health Organization underscores that no level of alcohol consumption is entirely safe, as potential negatives often outweigh positives.
"Inflammation is a key factor in heart disease," Professor Zabetakis concludes. "By incorporating anti-inflammatory foods into your diet, you can support heart health and lower cardiovascular disease risk by optimising the HDL-to-LDL ratio in your body."



