An NHS doctor has issued an urgent warning regarding the proper administration of several widely used medications, emphasising that incorrect timing with food can lead to severe health complications. Dr Kasim Ahmed, a specialist in geriatric and general internal medicine, appeared on BBC's Morning Live to discuss this prevalent issue, which he observes regularly in clinical practice.
The Critical Importance of Empty-Stomach Medications
Dr Kas, as he is commonly known, explained that certain medications must be taken on an empty stomach to ensure effective absorption and immediate therapeutic effects. He specifically highlighted levothyroxine, a thyroid replacement drug prescribed for autoimmune thyroid conditions like hypothyroidism.
"The number of people I see on huge, whacking doses of some of these medications because they're taking them with food so they're not being absorbed properly is really apparent," Dr Kas stated. He elaborated that levothyroxine is absorbed rapidly in the stomach but can become entangled with food particles, passing through the digestive system without being properly assimilated into the body.
Considerations for Fasting Periods
Dr Kas also addressed the importance of medication timing during religious fasting periods such as Ramadan and Lent. He advised patients to carefully plan when they take their drugs, suggesting that empty-stomach medications should be consumed with the pre-dawn meal during Ramadan, while full-stomach drugs should be taken after breaking the fast in the evening.
"The big thing here is really having a chat to your medical professional," he emphasised, urging individuals to seek personalised advice from healthcare providers to avoid potential health risks.
Medications That Require Food Intake
Conversely, Dr Kas warned that other common medications should never be taken on an empty stomach due to the risk of serious gastrointestinal complications. He specifically mentioned non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and naproxen, which are notorious for causing gastric acid issues and potentially dangerous stomach ulcers.
"Those are notorious for causing issues with gastric acid, potentially causing stomach ulcers, which can be really, really dangerous," he cautioned. He added that steroids, which similarly increase stomach acid production, and aspirin should also be taken with food to mitigate these risks.
Special Considerations for Diabetic Medications
Dr Kas also highlighted diabetic medications, noting that some, like metformin, can cause significant gastrointestinal side effects including nausea, diarrhoea, and vomiting when taken without food. Additionally, certain diabetes drugs that lower blood sugar levels require concurrent food intake to prevent dangerous hypoglycaemic episodes.
The NHS confirms that ibuprofen, a widely available painkiller that reduces inflammation and swelling, carries more side effects than paracetamol and is a major contributor to stomach ulcer development when taken improperly. Similarly, low-dose aspirin, used to prevent heart attacks and strokes in high-risk patients, and naproxen, another NSAID for joint and muscle pain, must be taken with food to avoid adverse effects.
Dr Kas's warning underscores the critical importance of proper medication administration timing, urging all patients to consult their medical professionals for personalised guidance to ensure both safety and efficacy in their treatment regimens.



