The second instalment of the planned trilogy, 28 Years Later: The Bone Temple, has hit UK cinemas and concludes with a dramatic showdown. The film picks up directly after the cliffhanger of 28 Years Later, following Alfie Williams's Spike as he encounters a violent gang known as the Jimmies. Meanwhile, Ralph Fiennes's Dr Kelson experiments on an Alpha infected named Samson, played by Chi Lewis-Parry.
In the final act, Jack O'Connell's Sir Jimmy Crystal leads his gang to Kelson, who pretends to be the devil at Crystal's request. However, when Kelson sees Spike among the masked Jimmies, he betrays Crystal by ordering the gang to crucify him. Crystal fatally stabs Kelson, but his betrayal prompts Jimmy Ink (Erin Kellyman) to turn against him. She kills the loyal Jimmies, allows Spike to stab Crystal, and crucifies Crystal upside down. Spike and Jimmy Ink (revealed to be Kelly) leave together.
Earlier, Kelson had been testing drugs on Samson, creating a cocktail of anti-psychotic medication. Samson recovers and returns to an abandoned train where he fights off other infected. He then finds Kelson dying and thanks him, allowing Kelson to see his success before dying. Samson approaches the crucified Crystal, who sees him as the devil.
The final scene cuts to the cottage from 28 Days Later, where Cillian Murphy's Jim is helping his daughter with her history exam. They hear a noise and see Spike and Kelly being chased by a horde of infected. Armed with a gun, Jim confirms to his daughter that they will help, setting up the third film in the trilogy.
