Dr Roger Henderson, a GP with over 40 years of experience, is urging the 8.9 million people in England prescribed antidepressants to be aware that their medication may contribute to night sweats, especially during hot weather. While many attribute broken sleep to the heatwave, Dr Henderson notes that certain antidepressants can make the body more prone to overheating and excessive sweating.
How Antidepressants Affect Body Temperature
Dr Henderson explains that antidepressants such as SSRIs (e.g., fluoxetine, sertraline, citalopram) and SNRIs (e.g., venlafaxine, duloxetine) influence serotonin and noradrenaline, which regulate mood but also control body temperature and sweat production. When these pathways are altered, some people become more susceptible to sweating. During a heatwave, the body already works harder to cool down, and the combination can lead to significant discomfort at night.
The Impact of Repeated Sleep Disruption
While one or two uncomfortable nights may not have lasting effects, several weeks of disturbed sleep can lead to persistent fatigue, difficulty concentrating, and reduced refreshment. Dr Henderson warns that it is easy to blame the weather alone, but if medication is also contributing, it is important to recognize this rather than simply struggling through.
Do Not Stop Antidepressants Suddenly
Dr Henderson emphasizes that patients should never stop taking antidepressants without medical advice, as sudden withdrawal can cause dizziness, flu-like symptoms, anxiety, nausea, and worsening sleep disturbance, and may increase the risk of depression relapse. If night sweats are frequent or affecting quality of life, patients should consult their GP or pharmacist. Adjustments such as changing the dose, timing of medication, or switching to an alternative treatment may help, but these should only be done under medical supervision.
When to Seek Medical Help
Dr Henderson advises that anyone experiencing night sweats along with unexplained weight loss, persistent fever, chest pain, confusion, fainting, or severe dizziness should seek prompt medical assessment, as these may indicate another underlying condition.
Tips for Managing Night Sweats Without Changing Medication
To reduce discomfort without altering medication, Dr Henderson recommends keeping blinds closed during the hottest part of the day, ventilating the bedroom when temperatures drop, and wearing loose, breathable nightwear. Lighter bedding, such as a summer duvet or cotton sheet, can also help. Staying hydrated throughout the day is important, but avoiding large drinks before bed can prevent sleep disruption from bathroom visits.
