NHS GP Dr Amir Khan Issues Critical Warning on Omeprazole Use
ITV's resident doctor and NHS GP, Dr Amir Khan, has issued an important warning to individuals taking the widely prescribed medication omeprazole for acid reflux and heartburn. The drug, a proton pump inhibitor (PPI), is commonly used to manage excess stomach acid, which can lead to conditions such as stomach ulcers and persistent digestive discomfort.
Understanding Omeprazole and Its Function
Omeprazole operates by reducing stomach acid production, providing symptom relief and allowing damaged digestive tissues to heal. While effective, complete alleviation of symptoms may require consistent use over several days to weeks, depending on the specific condition being treated. Long-term use is generally deemed safe under medical supervision, but Dr Khan emphasizes that extended periods of usage carry potential risks due to decreased stomach acid levels.
Dr Khan's Three Common Side Effects Alert
In a recent Instagram post, Dr Amir Khan, who boasts 788,000 followers, shared educational content highlighting the dangers of prolonged medication use. He stated, "All meds can have possible side effects. Here are some things you need to know and what to do." In an accompanying video, he detailed three common side effects associated with long-term omeprazole use.
First, nutrient absorption issues: Prolonged use can impair the body's ability to absorb essential vitamins and minerals, specifically vitamin B12, magnesium, and calcium. This deficiency may result in fatigue, weakened bones, and an increased risk of conditions like osteoporosis. Dr Khan advises ensuring a diet rich in green leafy vegetables, nuts, and dairy to mitigate these effects.
Second, infection susceptibility: Reduced stomach acid levels can compromise the body's natural defense against harmful bacteria, elevating the risk of infections such as Clostridioides difficile (C.diff), which causes severe diarrhoea. There is also a potential short-term increased risk of pneumonia, though long-term evidence remains unclear.
Third, bone and kidney health concerns: Extended use, particularly at high doses for a year or more, has been linked to a higher probability of bone fractures in areas like the hip, wrist, or spine due to diminished calcium absorption. Additionally, long-term usage is associated with an elevated risk of chronic kidney disease (CKD) and the development of benign stomach growths known as fundic gland polyps.
Practical Advice from Dr Khan
Dr Khan stresses that individuals should not abruptly discontinue their medication. Instead, he recommends consulting with a GP or pharmacist if concerns arise. He suggests that for those with well-controlled symptoms, reducing the dosage or using omeprazole intermittently might be viable options, but only under medical guidance. Regular monitoring of vitamin levels is also advised for long-term users to prevent deficiencies.
This warning serves as a crucial reminder for the millions relying on omeprazole to manage digestive issues, underscoring the importance of informed usage and proactive healthcare discussions.



