A GP has issued a heatwave warning to anyone taking widely prescribed antidepressants this summer, as elevated temperatures can create complications for patients. The UK is experiencing a marked geographical split, with the mercury climbing to a scorching 32C in the southeast, while the north contends with rainfall and considerably cooler conditions of around 14C.
Heat Health Alert Issued
An Amber Heat Health Alert has been issued across England as an intense summer heatwave is forecast to strengthen over the coming days. The Met Office predicts more settled conditions heading into the weekend as high pressure begins to establish itself from the south. "Sunny spells and feeling increasingly hot with temperatures well above the June average," the forecaster stated.
Risk for Antidepressant Users
Millions of people taking widely prescribed antidepressants have been cautioned they may face heightened risk of dehydration and heat exhaustion as temperatures climb across the UK. Selective Serotonin Reuptake Inhibitors, commonly known as SSRIs, are primarily prescribed to treat mental health conditions and function by boosting serotonin levels in the brain.
Around 8.7 million people in the UK received SSRI prescriptions between 2023 and 2024. Dr Rupa Parmar, GP and Medical Director at Midland Health, is providing comprehensive guidance on taking the medication during the summer months, reports the Mirror.
Why SSRIs Increase Heat Sensitivity
Dr Rupa Parmar explained: "Excess sweat is one of the most common side effects of antidepressants. It's most likely due to how the medication affects the hypothalamus, a brain part that plays an important role in regulating body temperature."
She continued: "Excess sweating can also cause dehydration, and there is a higher risk of heat exhaustion as heat tolerance is much lower. Signs of heat exhaustion include headaches, nausea, dizziness, weakness, irritability, and an increased body temperature."
Recognizing Heat Exhaustion and Heatstroke
Dr Rupa Parmar states: "For people on SSRIs, knowing the symptoms is crucial. If someone is experiencing heat exhaustion, get them out of the heat, keep them hydrated, and use cold compresses to help them cool down."
Heatstroke occurs when the body is completely unable to regulate its temperature, which can lead to serious organ damage. It has the same symptoms as heat exhaustion, as well as confusion, seizures, and a rapid heart rate and breathing. "The difference is that the symptoms of heat exhaustion usually subside within half an hour. If you are concerned someone has heatstroke, seek medical attention as quick treatment is necessary to prevent serious complications."
Tips to Avoid Heat-Related Issues
The doctor says: "Your body loses a lot of water from sweating, so to combat dehydration, drink at least three litres daily to regulate a normal body temperature. Caffeine and alcohol also increase urine production, so avoid these during the heat and stick to water."
She advises minimising time spent in direct sunlight, restricting outdoor activities to the cooler periods of early morning and late evening. When venturing outside, opting for loose-fitting garments made from breathable materials such as cotton and linen can help prevent your body from overheating.
"Cold compresses on the forehead and neck are also good for cooling down," she added. Those taking antidepressants may also experience night sweats and hot flushes, which can make getting a decent night's sleep particularly uncomfortable.
Keeping Your Home Cool
To lower the temperature in your bedroom, keep windows, blinds and curtains shut throughout the day to block out the warm air, opening them once the outside temperature has dropped after dark. She suggests: "If your room is under 35C, you could use a fan, and for the rest of your home, try to limit how long appliances like ovens and washing machines are on, as they can generate a lot of heat. If sweat is a problem getting in the way of your day-to-day life, it could be that your antidepressant isn't right for you."
SSRIs are rarely one-size-fits-all, and it can take a while to find the one that works the best for your needs and with minimal side effects. Never come off your medication without consulting your doctor first, and always talk to your GP if you're experiencing any worrying side effects.



