A major new study has found no evidence that taking paracetamol during pregnancy increases the risk of autism, ADHD or intellectual disability in children. The research, published in the Lancet Obstetrics, Gynaecology and Women's Health, directly contradicts claims made by former US President Donald Trump in September last year.
Trump had said that taking the painkiller, known as Tylenol in the US, was dangerous for pregnant women and urged them to avoid it. His remarks were condemned by medical organisations worldwide and caused anxiety among expectant mothers, as paracetamol is the recommended pain and fever treatment during pregnancy.
The systematic review, led by Professor Asma Khalil of City St George's, University of London, analysed 43 previous studies involving hundreds of thousands of children. It found no causal link between paracetamol use in pregnancy and neurodevelopmental conditions, concluding that genetic and familial factors are more likely explanations for any observed associations.
Professor Khalil said: 'The message is clear: paracetamol remains a safe option during pregnancy when taken as guided. This is important as paracetamol is the first-line medication we recommend for pregnant women in pain or with a fever.' The researchers hope the review will end scepticism about using the drug during pregnancy.
UK Health Secretary Wes Streeting had previously advised women to ignore Trump's claims. Experts welcomed the study, with Professor Grainne McAlonan of King's College London saying she hopes the findings bring the matter to a close.
