Many people rely on medications for various health conditions, but combining certain drugs can pose serious risks, a pharmacist has warned. Abbas Kanani from Chemist Click highlighted five combinations to avoid, as they may lead to increased side effects, organ damage, or reduced effectiveness.
The first dangerous mix is over-the-counter anti-inflammatory drugs like ibuprofen or naproxen with blood thinners such as warfarin. This combination increases the risk of bleeding, particularly gastrointestinal bleeding, as both affect blood clotting.
Second, certain antibiotics like erythromycin or clarithromycin should not be taken with statins. This can raise the risk of muscle damage known as rhabdomyolysis, as antibiotics can increase statin concentrations in the blood.
Third, triptans used for migraines together with selective serotonin reuptake inhibitors (SSRIs) for depression may cause serotonin syndrome. Symptoms range from mild shivering and diarrhoea to severe muscle rigidity, fever, and seizures.
Fourth, oral contraceptives can be less effective when taken with some antibiotics, such as rifampin. Finally, antacids can prevent the absorption of antibiotics like tetracycline or ciprofloxacin; these should be taken two hours before or four hours after acid reflux medication.
Kanani advises always consulting a GP or pharmacist before combining medications and having regular check-ups to monitor effects and adjust dosages if needed.
