NHS CAR-T Therapy Breakthrough: 28-Year-Old First to Receive Pioneering Cancer Treatment
First NHS patient gets pioneering CAR-T cancer therapy

In a landmark moment for UK healthcare, a 28-year-old man has become the first patient on the NHS to receive a pioneering new cancer treatment after his aggressive leukaemia returned. Oscar Murphy appeared on BBC Breakfast on Wednesday, 14 January 2026, to share an emotional update on his battle with acute lymphoblastic leukaemia and the groundbreaking CAR-T therapy that is offering him new hope.

A Revolutionary 'Sci-Fi' Treatment on the NHS

Oscar Murphy's cancer journey took a dramatic turn when his acute lymphoblastic leukaemia, a form of blood cancer, returned despite extensive previous treatment. Facing a disease his doctor described as "really aggressive", Oscar was rapidly transitioned to a new experimental therapy known as CAR-T.

This innovative method works by reprogramming the patient's own immune cells to recognise and attack cancer cells. "It was such a quick transition," Oscar explained to BBC Breakfast hosts Sally Nugent and Jon Kay. "I went from basically being in remission to it coming back to this new experimental treatment in the space of about a month." He marvelled at the process, calling it "very sci-fi" but holding the potential for a permanent cure.

Doctors Hail a Life-Extending Breakthrough

Oscar's consultant haematologist, Dr Eleni Tholouli, joined the programme to underscore the treatment's significance. She stated that without this therapy, patients with this type of aggressive leukaemia typically "don't live beyond six to eight months." CAR-T therapy changes that prognosis radically.

"With this therapy, we can offer them years and potentially a cure, so it's naturally very significant," Dr Tholouli said. "This is, of course, revolutionising the way we tackle this cancer." She emphasised the speed required for Oscar's care, noting everything had to move "very, very fast" once his cancer returned.

Looking to the Future with New Hope

Speaking via video link from the Manchester Royal Infirmary, Oscar shared that he currently feels "fine" following the treatment. His outlook is now firmly fixed on the future. Last month, he and his partner Lauren tied the knot in a hospital ceremony, and they are now making plans for a life together.

"I want children, I want the white picket fence with my amazing wife and I just want that normality," Oscar expressed emotionally. "I want to go back to my job that I love and just be back normal. This is my gateway to doing it and I can't wait."

His appearance on BBC Breakfast served as a powerful testament to both the human impact of medical innovation and the vital role of the NHS in delivering cutting-edge care. For more information and support on cancer, visit the Macmillan Cancer Support website.