Investigators working on the disappearance of Nancy Guthrie have announced that DNA evidence recovered from gloves discovered near her Arizona home has failed to produce any matches within the national database. This development marks a significant setback in the ongoing search for the 84-year-old mother of NBC "Today" co-anchor Savannah Guthrie.
No DNA Hits in CODIS System
The Pima County Sheriff's Department confirmed on Tuesday, February 17, 2026, that there were no DNA hits in the Combined DNA Index System (CODIS) from the gloves. "At this point, there have been no confirmed CODIS matches in this investigation," the department stated, indicating that other DNA samples have also been processed through the system without success.
CODIS serves as a crucial repository for DNA collected from crime suspects and individuals with convictions. Any matches could have potentially identified suspects linked to Guthrie's disappearance, making this lack of hits a notable obstacle for law enforcement.
Details of the Disappearance
Nancy Guthrie was reported missing from her Tucson-area home on February 1, 2026, after spending the previous evening with family. Police revealed that her blood was detected on the porch of her residence, heightening concerns about her welfare.
Surveillance footage from a porch camera captured a man wearing a ski mask, long pants, a jacket, and gloves, carrying a backpack. The FBI has described the suspect as approximately 5 feet, 9 inches tall with a medium build. The gloves found about 2 miles from Guthrie's home appear to match those worn by the individual in the video, according to FBI analysis.
Additional Evidence and Search Efforts
Authorities have disclosed that there is additional DNA evidence collected from Guthrie's residence, which is currently undergoing analysis. In parallel, investigators are collaborating with manufacturers and experts to locate Guthrie by detecting signals from her heart pacemaker.
Reports indicate that a "signal sniffer" device has been attached to low-flying aircraft as part of this technological effort to trace her whereabouts.
Family Appeal for Information
Savannah Guthrie made a heartfelt appeal via an Instagram video on Sunday, urging anyone with information about her mother's disappearance to come forward. "It is never too late to do the right thing," she said. "And we are here. And we believe in the essential goodness of every human being, that it's never too late."
The investigation remains active, with authorities continuing to pursue all leads in the hope of resolving this distressing case.
