A new study has raised concerns about the widespread use of omeprazole, a medication taken by millions for acid reflux, suggesting that up to two-thirds of people with suspected acid reflux may not actually have the condition and could be taking the drug unnecessarily. However, Dr Xand, speaking on BBC's Morning Live on May 26, urged caution and advised against acting on the study's findings.
Dr Xand highlighted several shortcomings of the research, including its limited participant group, the involvement of a gut testing company, and the fact that it has not been published in a peer-reviewed journal. He warned that stopping the medication suddenly could lead to a rebound overproduction of acid, worsening symptoms and causing further problems.
Despite potential side effects from long-term use, Dr Xand emphasised that omeprazole is extremely safe, with a very small increased risk of gut infections (0.4 per cent). He noted that the benefits, such as preventing dangerous bleeds, often outweigh the risks. He advised patients to have regular reviews with their doctor for any long-term medication and to consult their GP before stopping omeprazole.
In the UK, omeprazole and other proton pump inhibitors (PPIs) are available on prescription or over the counter at pharmacies. The NHS warns against taking omeprazole for longer than two weeks without a prescription and advises seeing a GP if symptoms persist or worsen. Common side effects include headaches, stomach pain, nausea, and diarrhoea.



