The NHS has issued a warning about potentially serious side effects associated with Bisoprolol, a widely prescribed beta-blocker used to treat heart and circulation conditions. Millions of people across the UK rely on this medication, with over 50 million prescriptions issued annually. Bisoprolol is the seventh most prescribed medication in England, according to NHS England, with 32 million prescriptions in 2024-25 alone.
What Is Bisoprolol?
Bisoprolol is a beta-blocker commonly prescribed for high blood pressure, angina, atrial fibrillation, and other conditions causing irregular heartbeat. It works by slowing the heart rate and making it easier for the heart to pump blood. The NHS states: "If you have high blood pressure, taking bisoprolol helps prevent future heart disease, heart attacks and strokes."
Common Side Effects
While many side effects are mild and temporary, affecting more than one in 100 users, the NHS advises first-time users to take the medication at bedtime to avoid dizziness. Common side effects include:
- Feeling dizzy or sick
- Headaches
- Cold hands or feet
- Constipation
- Diarrhoea
Serious Side Effects: When to Seek Help
Rare but serious side effects require immediate medical attention. The NHS advises calling a doctor or NHS 111 if you experience:
- Shortness of breath with a cough that worsens with exercise (e.g., walking up stairs)
- Swollen ankles or legs
- An irregular heartbeat
- Yellowing of the whites of the eyes or skin (signs of liver problems)
When to Dial 999 Immediately
Call 999 if you experience chest pain, which could indicate heart problems, or shortness of breath, wheezing, and chest tightness, which may signal lung problems. Additionally, dial 999 if you have signs of a serious allergic reaction (anaphylaxis), including:
- Sudden swelling of the lips, mouth, throat, or tongue
- Rapid or difficult breathing (wheezing, choking, or gasping)
- Tightness in the throat or difficulty swallowing
- Blue, grey, or pale skin, tongue, or lips (on brown or black skin, check palms or soles)
- Sudden confusion, drowsiness, or dizziness
- Fainting that cannot be roused
- A child becoming limp, floppy, or unresponsive
The NHS adds: "You or the person who's unwell may also have a rash that's swollen, raised, itchy, blistered or peeling. These can be signs of a serious allergic reaction and may need immediate treatment in hospital." Do not drive yourself to A&E; call 999 for advice.
