Doctor Ranj Singh has reminded Britons taking selective serotonin reuptake inhibitors (SSRIs) to be aware of two potential side effects: suicidal thoughts and sexual dysfunction, which can persist after stopping the medication. Speaking on BBC Morning Live, he stressed that patients should never alter their medication without consulting a doctor first.
Common SSRIs and their uses
Common variants include fluoxetine, sertraline and citalopram, the doctor explained. According to the NHS, SSRIs are the most widely used type of antidepressants and are usually the first type prescribed because their side effects are "generally easier to manage, and they are less likely to cause serious problems if you take too much of the medicine".
The NHS notes that these medications can treat several conditions. Citalopram is used for depression and panic disorder. Sertraline can treat depression, obsessive-compulsive disorder (OCD), panic disorder, post-traumatic stress disorder (PTSD) and social anxiety disorder. Fluoxetine is used for depression, bulimia and OCD, and sometimes for menopause symptoms.
Doctor's warning on side effects
Speaking to hosts Gethin Jones and Gaby Roslin, Dr Ranj said: "Lots of people take antidepressants for various reasons. We know that they can be life-saving, but we also know that some of them have potentially significant side effects. This is just a reminder of that for a specific type of antidepressant called an SSRI."
He added: "It's just a reminder that people need to be aware of this and if you happen to be having any of these symptoms, please speak to a healthcare professional. You should not be making changes to your medication off your own back. Just be aware of it, doesn’t mean you’re going to get it, but if you do, please speak to someone."
Government safety update and support
The UK Government issued an update on October 15, stating that "new safety measures are now being implemented to improve how the risks of suicidal thoughts and behaviours and persistent sexual dysfunction are communicated to patients taking antidepressant medications."
In advice published by the Medicines and Healthcare products Regulatory Agency, health professionals are urged to tell patients to seek urgent medical advice if they have "new or worsening suicidal thoughts, particularly when starting or changing the dose". Patients can seek help at NHS 111, talk to their local mental health crisis team, call Samaritans on 116 123, or text "SHOUT" to 85258. More information and support options are available on the NHS website.