Medik8 has introduced a new serum featuring a vegan-friendly version of polynucleotides, a popular ingredient in skincare and aesthetic treatments. Known as polydeoxyribonucleotide (PDRN), this compound is traditionally sourced from salmon DNA and is believed to stimulate collagen production and repair the skin barrier. Previously confined to in-clinic facials, the ingredient is now available for home use in Medik8's exo-PDRN prismatic+ youthful vitality serum.
How the Serum Works
The serum is designed for application after cleansing, with the brand claiming that its form of PDRN penetrates deeply into the skin layers to provide soothing and smoothing benefits. The formula also includes other advanced ingredients such as a triple exosome complex and GF mini protein, which are intended to support skin barrier health and boost collagen and elastin production.
Two-Week Test by a Beauty Expert
Helen Wilson-Beevers, a 42-year-old beauty journalist and mother with dry, sensitive skin, tested the serum for two weeks. She incorporated it into her daily skincare routine, applying it both morning and evening after cleansing. The serum has a glossy, slightly runny consistency that glides on easily and offers a cooling, refreshing sensation. Although it takes a few seconds to absorb, it leaves no residue, only a softened skin feel.
After one week of twice-daily use, Wilson-Beevers observed that her skin appeared smoother and more even in texture, with increased brightness and radiance. Despite her skin's tendency to be reactive and prone to irritation, she experienced no sensitivity from the serum. Instead, her skin felt soft and hydrated, with ingredients promising long-term barrier protection.
Results and Value
While the serum carries a premium price tag of £79 for 30ml, Wilson-Beevers found the results impressive. She noted improvements in hydration, luminosity, and smoothness, as well as overall texture and tone. Although she cannot yet comment on long-term collagen benefits, she plans to continue using the serum twice daily and is eager to see further results over time.
Key Specifications
- Size: 30ml
- Formula type: Serum
- Key ingredients: PDRN, exosome complex, glycerin, niacinamide
- Suitable for: All skin types
- Price: £79 from Medik8.com
Is It Worth It?
The Medik8 exo-PDRN prismatic+ youthful vitality serum delivers a refreshing, smoothing finish that improves skin tone and texture. While it is a luxury product, the visible results after two weeks have earned it a permanent place in the tester's daily routine. Long-term effects remain to be seen, but the initial benefits are promising.
Testing Methodology
Wilson-Beevers evaluated the serum based on its formula, application, and results. She assessed key ingredients and their potential benefits, used the serum consistently after cleansing, and monitored changes in skin texture, firmness, and tone. With over a decade of experience testing skincare products, she provides expert insight into the serum's efficacy for anti-ageing and skin health.



