The NHS is urging patients taking amlodipine, a common blood pressure and angina medication, to call 111 if they experience sudden severe tummy pain, which could indicate acute pancreatitis. This rare but serious side effect requires immediate medical attention.
What is Amlodipine?
Amlodipine is a prescription drug that relaxes and widens blood vessels, improving blood flow. While effective, it can cause side effects, some of which are serious. The NHS warns that acute pancreatitis—swelling of the pancreas—is one such rare side effect.
Symptoms of Acute Pancreatitis
Acute pancreatitis causes sudden, severe tummy pain that does not go away. Additional symptoms may include a high temperature, nausea, or vomiting. The pain may:
- Start suddenly and persist
- Be severe, sharp, or knife-like
- Affect the upper abdomen, one side, or the whole stomach
- Spread to the sides and back
- Worsen after eating, moving, or lying down
- Improve when leaning forward or bringing knees to the chest
Other Serious Side Effects
The NHS also lists other serious but rare side effects of amlodipine, including anaphylaxis (swollen throat/tongue, rash, breathing difficulty) and Stevens-Johnson syndrome (skin blistering, sores, flu-like symptoms). Very rarely, amlodipine may cause heart attacks.
When to Seek Help
The NHS advises: “If you're taking amlodipine and think you might be having serious side effects, call NHS 111.” Do not delay seeking medical advice.
Common Side Effects
More common but less serious side effects include swelling in the ankles/feet (oedema), headaches, dizziness, sleepiness, palpitations, flushing, tummy pain, nausea, constipation, diarrhoea, and fatigue. The NHS warns: “If you feel dizzy or sleepy after taking amlodipine, do not drive, ride a bike, or use machinery until you no longer have these symptoms.” Speak to a pharmacist or doctor if side effects persist.
