Urgent health warnings have been issued ahead of what promises to be a record-breaking Bank Holiday weekend, with temperatures expected to soar to 33°C. Britons taking common antidepressants such as Sertraline, Citalopram, and Fluoxetine are being urged to take extra precautions as these medications can interfere with the body's ability to regulate temperature.
The UK Health Security Agency (UKHSA) has issued yellow heat warnings across several regions, effective from 9 am on May 22 until 5 pm on May 27. The warnings cover the East Midlands, West Midlands, East of England, London, and the South East, where vulnerable individuals face a greater risk to life.
According to Mental Health UK, certain antidepressants, including selective serotonin reuptake inhibitors (SSRIs) like Sertraline, Citalopram, and Fluoxetine, as well as serotonin-noradrenaline reuptake inhibitors (SNRIs) and antipsychotic medications, can affect temperature regulation. This side effect is often listed in medication leaflets, and patients are advised to review them carefully.
Dr. Sameer Sanghvi, a GP and Clinical Technology Lead at LloydsPharmacy Online Doctor, explained: "Common antidepressants can all stop the temperature-regulating area of the brain from functioning as it should. SNRIs are known to cause excessive sweating and dehydration, while SSRIs have been linked to heat intolerance and heat stroke." He emphasised that patients should not stop taking their medication without consulting a doctor and should take precautions to stay cool, such as staying in the shade, drinking plenty of fluids, avoiding alcohol, and wearing loose clothing.
The Met Office forecasts temperatures rising to 30°C on Saturday, 32°C on Sunday, and potentially 33°C on Monday, which could break the UK May record of 32.8°C. Deputy Chief Forecaster Steve Kocher noted that while much of the UK will enjoy dry and sunny weather, western Scotland and Northern Ireland may see more cloud and showers. Coastal areas may experience low cloud and sea fog.
This heatwave poses particular risks for those on antidepressants, older people, children, pregnant women, and individuals with underlying health conditions. The UKHSA urges everyone to stay hydrated, avoid the sun between 11 am and 3 pm, and refrain from strenuous exercise during the hottest parts of the day.



