NHS GP and TV doctor Dr Amir Khan has issued a warning about potential side effects of commonly prescribed medications, including omeprazole and bisoprolol. In a recent Instagram post, he highlighted five widely used drugs, urging patients to seek medical advice if they experience problems.
Common Medications and Their Side Effects
Dr Khan, known for appearances on ITV's This Morning and Lorraine, explained that when prescribing, doctors weigh benefits against risks. He advised: "When we prescribe medication, in our heads, we're always weighing up potential benefits versus risk of side effects. And we only give them when the benefits outweigh any risk. But if you're taking medication, having problems with them, don't just stop taking them. Come and talk to us because we often have lots of alternatives that we can give you."
He noted that metformin, used for type 2 diabetes, can cause digestive issues. "It works really well. But especially when you first start it, it can cause diarrhoea, bloating, stomach cramps, and nausea. For many people, these symptoms settle after a few weeks. So don't lose hope too quickly, but there are alternatives should you need it."
PPIs and Bisoprolol
Proton pump inhibitors (PPIs) like lansoprazole and omeprazole, which reduce stomach acid, are used to treat acid reflux, GERD, ulcers, and other conditions. Dr Khan warned that long-term use could reduce absorption of nutrients like vitamin B12 and magnesium, advising that they "should be reviewed from time to time."
Regarding bisoprolol, used for high blood pressure and heart problems, he mentioned side effects like tiredness, dizziness, and cold hands and feet. He advised: "Come and talk to us." NHS guidelines warn of rare serious risks, and patients are advised not to stop taking bisoprolol suddenly.
Blue Inhalers and Asthma
Dr Khan also discussed salbutamol blue inhalers, which can cause shaky hands or a racing heart. He emphasized that needing the blue inhaler regularly indicates poor asthma control and warrants a review. "The most important thing is this. If you're getting side effects from your medicine, don't suffer in silence and don't just suddenly stop taking them without speaking to your GP, nurse, or pharmacist."
Recent NICE guidance warns that prolonged use of blue inhalers can worsen asthma. Professor Ewan Maule said: "By upgrading to a combined treatment inhaler patients not only get the relief they need but also benefit from treatment that treats the root cause of their asthma." Nearly half of blue inhaler users were prescribed more than two in 2024-25.
Iron Tablets
Finally, Dr Khan mentioned ferrous sulfate (iron tablets), which can cause constipation, tummy discomfort, and nausea. He reassured that black stools are expected, and liquid iron is available as an alternative.
He concluded by recommending that any concerns be raised directly with a GP.
