BBC Health Expert Highlights Mortality Risks for Dementia Patients on Common Medications
A BBC health expert has raised concerns following a new study that indicates an increased risk of death for some individuals taking antidepressants or anti-anxiety medications, particularly those with dementia. The research, conducted by Queen’s University Belfast, suggests that drugs like Sertraline, Citalopram, and Fluoxetine, which are used by millions, may not always be suitable for people suffering from dementia.
Study Findings and Expert Insights
On BBC Morning Live, Dr Oscar Duke discussed the study, emphasizing that it focused on the impact of these medications on dementia patients. He noted that while the findings are concerning, they should not cause panic. The study, which analyzed data from Northern Ireland over a nine-year period from 2012 to 2020, involved 28,781 people living with dementia, with half dying during the follow-up.
Dr Duke explained that antidepressants were prescribed to 59.2% of individuals who died, and anti-anxiety medications to 44.8%. The research found a slight increase in mortality risk—around 8% over ten years—for those on antidepressants. However, the risk was significantly higher for anti-anxiety drugs like diazepam and lorazepam, with up to a 26% increase in mortality.
Understanding the Risks
The expert attributed the higher mortality with anti-anxiety medications to their sedating effects. As dementia progresses, patients may become more confused and drowsy, increasing the likelihood of falls and injuries such as fractures, which can severely impact life expectancy, especially in older adults. Dr Duke stressed that this does not mean patients should stop taking their medications abruptly but should consult healthcare professionals to reassess their need and benefits.
Broader Implications and Recommendations
Dr Catherine Sinnamon, lead author of the study, highlighted that dementia is a leading global cause of death with no effective cure, affecting over 55 million people worldwide. She emphasized the importance of improving health and quality of life while reducing social and economic costs. The study aims to ensure better treatment and care by understanding how these medications affect dementia patients.
Dr Heather Barry, principal investigator, added that the findings underscore the need for judicious prescribing and regular medication reviews by GPs or pharmacists for people with dementia. This is crucial as dementia prevalence is projected to rise with an aging population, currently affecting nearly 1 million people in the UK.
Key Takeaways
- Increased Mortality: Antidepressants show an 8% higher risk, while anti-anxiety drugs like diazepam and lorazepam show up to a 26% increase.
- Patient Advice: Do not panic; instead, discuss medication use with a healthcare provider to evaluate necessity and benefits.
- Study Scope: Focused on dementia patients in Northern Ireland, highlighting the need for cautious prescribing in this vulnerable group.
This research, supported by the Honest Broker Service in Northern Ireland, calls for heightened awareness and proactive management of medication in dementia care to safeguard patient well-being.
