The NHS has issued a cautionary note for the millions of people in the UK taking common blood pressure medications such as amlodipine, ramipril, or lisinopril. High blood pressure, or hypertension, affects around one in three adults in the UK, with many unaware of their condition due to its lack of symptoms. It is often called the 'silent killer' as it can lead to heart attacks, strokes, and kidney failure.
Two of the most prescribed medications for hypertension are ramipril, an ACE inhibitor, and amlodipine, a calcium channel blocker. In the past year, ramipril accounted for approximately 34.8 million prescription items, while amlodipine accounted for over 30 million. These drugs work by widening blood vessels or relaxing arteries to lower blood pressure.
The NHS warns that taking amlodipine alongside other blood pressure-lowering medicines such as ramipril or lisinopril can sometimes lower blood pressure too much. Symptoms of low blood pressure (hypotension) include dizziness, lightheadedness, blurred vision, fainting, nausea, and weakness, especially when standing up quickly. If these symptoms persist, patients are advised to consult their doctor, as their dose may need adjustment.
Additionally, the NHS advises caution with herbal remedies. St John's wort, a herbal treatment for depression, may affect how amlodipine works. Patients are urged to speak to their doctor before taking any herbal supplements, as these are not tested for interactions with prescription medicines.
For those concerned about their blood pressure or medication, the NHS recommends speaking to a GP. Lifestyle changes such as reducing salt intake, eating more fruits and vegetables, exercising regularly, and limiting alcohol can also help manage hypertension.



