BBC expert Dr Alexander van Tulleken, known as Dr Xand, has issued an update for people taking proton pump inhibitors (PPIs) such as Omeprazole and Lansoprazole. Speaking on BBC Morning Live, he addressed concerns about the safety of these widely used medications, which reduce stomach acid production and are taken by an estimated one in seven Britons.
Dr Xand explained that while PPIs are extremely safe overall, recent trials have found a very small increased risk of gut infections – around 0.4 per cent. He stressed that this risk is outweighed by the benefits, including preventing dangerous bleeds and reducing the risk of cancer. 'These medications are extremely safe,' he said. 'They are blockbuster drugs taken by billions of people worldwide.'
The doctor also warned against stopping PPIs suddenly, as this can cause a rebound effect where the stomach produces excess acid, making symptoms worse. He advised anyone on a prescription to speak to their GP before discontinuing use. The NHS similarly cautions against taking over-the-counter Omeprazole for more than two weeks without consulting a doctor.
Common symptoms of acid reflux include heartburn, a hoarse voice, bad breath, hiccups, bloating, and nausea, particularly when lying down or bending over after meals. Dr Xand emphasised that while the condition can be uncomfortable and carry long-term risks, PPIs remain a safe and effective treatment when used correctly.
