The M62 has been closed in both directions between Junction 20 at Rochdale and Junction 21 for Milnrow following a serious lorry crash, with traffic building rapidly on the major motorway.
The incident has led to around five miles of queues as drivers face disruption on one of the UK's busiest east-west routes.
Motorway Shut Between Junctions 20 and 21
The motorway was initially closed in both directions between Junction 20 at Rochdale and Junction 21 for Milnrow, according to reports.
Emergency services were called to the scene, although the full extent of any injuries has not yet been confirmed.
Drivers Advised to Expect Delays
Traffic is building on the motorway as a result of the closure, with motorists facing significant delays in the area.
Further updates on the reopening of the carriageways are expected as the situation develops.