Liverpool are without Dominik Szoboszlai and Jeremie Frimpong for their Champions League clash against Villarreal, but Cody Gakpo could start.
The Reds endured a frustrating trip to Brentford on Saturday despite picking up a turnaround 2-1 victory, with both Szoboszlai and Frimpong forced off with injuries.
Speaking ahead of the Villarreal match, Iraola confirmed the pair will both miss tonight's fixture, with Frimpong facing several weeks out but Szoboszlai's issue deemed less serious.
Midfield Reinforcements
As such, Ryan Gravenberch is reinstated into the midfield here, after he missed the Brentford trip due to serving a suspension.
He will slot back into the centre of the park at Anfield, partnering Alexis Mac Allister, while Trey Nyoni is a surprise starter.
Gakpo also makes his comeback on the left flank, while Lewis Koumas and Rio Ngumoha complete the front three.
Defensive Lineup
Ronald Araujo spoke alongside Iraola at the pre-match press conference, suggesting he was in line to start, and he slots in at right-back.
Kostas Tsimikas comes in at left-back, while Virgil van Dijk and Jeremy Jacquet shield Alisson.
Liverpool XI: Alisson; Araujo, Jacquet, Van Dijk, Tsimikas; Gravenberch, Mac Allister, Nyoni; Gakpo, Koumas; Ngumoha
Subs: Barcola, Chambers, Danns, Gomez, Isak, Kerkez, Laffey, Mamardashvili, McDonnell, Wirtz, Woodman
Injured: Szoboszlai, Frimpong, Ekitike, Leoni, Bradley
Ineligible: Chiesa, Endo
Time and date: 8pm BST on Tuesday October 20, 2026
Venue: Anfield
How to watch: Amazon Prime