The Ospreys travel to Tbilisi to take on Black Lion in their Challenge Cup opener, with kick-off at 1pm and the match streaming on EPCR TV.
Having started their season with two weeks in South Africa, Mark Jones' side now travel to Georgia, meaning they have racked up around 10,000 miles of travel in just four weekends of fixtures.
As such, the Ospreys have rotated heavily for their European curtain-raiser.
Team news and debutant
Wales U20s full-back Lewis Edwards makes his Ospreys debut in a completely new backline.
Owen Watkin returns to captain the side, partnering Wallabies centre Lalakai Foketi.
Another Australian import, Lawson Creighton, is handed a start in the fly-half jersey.
Pack changes
In the pack, only Ryan Smith remains from the starting forwards at Rodney Parade last Friday.
Lewis Jones partners him in the boiler room, behind a front-row of Steffan Thomas, Lewis Lloyd and Ben Warren.
In the back-row, Huw Sutton packs down at blindside, with Gwilym Evans on the openside and Morgan Morse at No. 8.
Teams and how to follow
Ospreys: Lewis Edwards; Luke Morgan, Owen Watkin (c), Lalakai Foketi, Iestyn Hopkins; Lawson Creighton, Reuben Morgan-Williams; Steffan Thomas, Lewis Lloyd, Ben Warren, Lewis Jones, Ryan Smith, Huw Sutton, Gwilym Evans, Morgan Morse.
Replacements: Efan Daniel, Cameron Jones, Kian Hire, Ben Roberts, Morgan Morris, Luke Davies, Harri Wilde, Evardi Boshoff.
The match kicks off at 1pm, with EPCR TV streaming it. You can also follow the match in the live blog below.