Cancer Research UK has announced the closure of 190 of its shops across Britain as part of a major restructuring programme, citing rising costs and changing shopping habits. The charity has already shut several stores, with the first wave of 90 closures expected to be completed by the end of this month, and a further 100 to close by April 2027.
The charity first outlined the retail shake-up in October 2025, warning of mounting financial pressures on high street operations. Shops were selected for closure based on financial performance, lease agreements, and their geographical position within the wider retail network. Rising operational costs, inflationary pressures, declining footfall, and competition from online resale platforms were cited as key factors.
Cancer Research UK also closed its online marketplace earlier this year, ceasing sales of pre-owned items through external resale websites. Despite the closures, the charity will continue to operate 320 higher-performing shops and plans to open 12 new out-of-town superstores, targeting shoppers seeking larger, value-focused retail spaces.
Chief Executive Michelle Mitchell acknowledged the impact on staff, volunteers, and communities, stating: 'Without action, we predict many of our shops will become unprofitable. A smaller, high-performing retail operation will mean we will fund more life-saving cancer research and better serve our customers, staff and volunteers.' The restructuring is expected to generate an additional £12.4 million for scientific research over the next five years.
The charity emphasised that its retail operation has 'played a critical role in our mission, delivering over £225m in contribution over the last 10 years.' In its 2024/25 annual report, Cancer Research UK reported spending £403 million on research in the previous year and remains on track to exceed its commitment of £1.5 billion over five years.
