The A19 northbound is closed near Sunderland after a double crash overnight, with police investigation work under way at the scene.
National Highways said the incident occurred before 4.35am and is described as an initial collision between two vehicles, with a further collision following the arrival of emergency services.
Road closed near Herrington Interchange
The road is closed northbound from the A690 junction, the Herrington Interchange, south of the interchange itself. One lane is closed.
The police are understood to be carrying out investigation work at the scene.
Further updates
More details are expected to follow as the situation develops.